Hyvisc is a clear, colorless, viscous fluid contained in a 5 mL disposable syringe, as a single 2 mL dose. Chemically hyaluronic acid is a high molecular weight mucopolysaccharide composed of repeating disaccharide units, each unit consisting of D-glucuronic acid and N-acetyl-D-glucosamine. Each mL of Hyvisc injections contains 11 mg hyaluronate sodium, 8.47 mg of sodium chloride, USP, in sterile water for injection, USP q.s.

Maintains viscoelasticity and lubrication properties similiar to naturally occuring synovial fluid.

The recommended dose of Hyvisc is 2 mL ( 22 mg) given to horses intra-articularly in small and medium-sized joints (carpal, fetlock). In larger joints (hock), the dosage is 4 mL (44 mg). Treatment may be repeated at weekly intervals for a total of three treatments. As with any intra-articular injection, aseptic technique is used. Precautions Store under refrigerated conditions. Protect from freezing and avoid excessive heat. Used or partially used syringes should be crushed and disposed of in an appropriate landfill. Federal law restricts this drug to use by or, on the order of a licensed veterinarian.

Hyvisc is recommended for treatment of joint dysfunction in horses due to non-infectious synovitis associated with equine osteoarthritis.

Not for use in horses intended for food. Do not administer intravascularly. Do not use if numerous small air bubbles are present throughout the solution. See package insert for complete information.